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Final Fantasy Online Forums  >  Community Discussion  >  General Discussion

That cure for Aids/HIV? Apparently legit.





0
 06.10.2012 8:08am
Thread Creator

Arckanghel
Pirate.



https://www.dailymail.co.uk/health/article-2156697/How-man-cured-AIDS-inspired-doctors-discover-revolutionary-new-treatment.html

So The Berlin Patient as the original person cured is known is doing well and two others are on deck in further tests. The mechanism is transplanted material from rare individuals who are resistant or possibly immune from HIV.




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0
 06.10.2012 4:51pm


Crusader
Not Even My Dad Hit Me



Fucking awesome!








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0
 06.10.2012 5:11pm


Crux
A mental Dentist's office



That is Fan-freaky-deaky-tastic!

I'm sure there are going to be plenty of hurdles in this until they find a process that is easily repeatable and not as painful. As in the harvesting of these cells I mean.




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0
 06.10.2012 5:21pm


Testament
Shamshot



CCR5, huh? Amazing.








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0
 06.10.2012 5:27pm
 (Edited on 06.10.2012 at 5:33pm)

Zubis
Registered Member



Requires umbilical cord blood from Swedes? Well I'm willing to do my part to increase the Swedish population.

Seriously though, while it's very heartening to know we have a cure, it doesn't seem to be something that can be mass produced?




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0
 06.10.2012 5:30pm


Southern Comfort
silently judging all of you



Not a perfect cure - gutting and replacing a person's immune system with another resistant immune system seems like a pretty drastic step - but hey, one step closer.




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0
 06.10.2012 6:51pm


OrionHardy
Otherworld



Reading that article, I didn't get the impression of gutting and replacing the immune system. I got the impression that it's updated, like adding a sercuity patch on a computer.



Great men aren't everywhere, just where it counts.

If you ever see me online playing Halo, join me please.




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1
 06.10.2012 7:41pm


Dh
Not in the face!
The Alpha and the Omega



I wouldn't put a whole lot of faith in this, especially when you're reading it from Daily Mail. AIDS gets cured several times a year, every year, it's on the news, and then nothing happens.



I made this for you!




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0
 06.10.2012 8:01pm


Spidey
So Sigh Ety



Dh said:

I wouldn't put a whole lot of faith in this, especially when you're reading it from Daily Mail. AIDS gets cured several times a year, every year, it's on the news, and then nothing happens.

this

Though it is worth noting all these cures ARE progress. and are probably special circumstance cures....so each one probably adds to our understanding




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0
 06.10.2012 8:32pm
Thread Creator

Arckanghel
Pirate.



Blood - March 10, 2011

Furthermore, during the process of immune reconstitution, we found evidence for the replacement of long-lived host tissue cells with donor-derived cells, indicating that the size of the viral reservoir has been reduced over time. In conclusion, our results strongly suggest that cure of HIV has been achieved in this patient.

https://www.ncbi.nlm.nih.gov/pubmed/21148083

BBC Interview with the virologist who won a Nobel for work in identifying HiV:

"The reason why we are talking about a cure today is because we have some evidence that it might be possible," Professor Barre-Sinoussi told Tim Franks on the BBC's HARDtalk programme.

https://news.bbc.co.uk/2/hi/programmes/hardtalk/9726339.stm

Obviosly there is a donor issue, but sounds very promising regardless of who is reporting it.




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0
 06.11.2012 2:22am


Atma Weapon
I Am Pure Energy

While this is interesting, a vaccine would be an infinitely bigger breakthrough. Most deaths from AIDS occur in indeveloped of developing countries where people can't afford food or the most basic medical care, much less multiple bone marrow transplants. A vaccine would be dramatically cheaper, and would cause no suffering to the patient.




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0
 06.12.2012 7:58am
Thread Creator

Arckanghel
Pirate.



I totally agree that it needs to become more accessible and at a lower cost. However, all the money saved, due to the high cost of HIV/AIDS treatments, might actually land in that bucket for researching a vaccine. A cure, no matter how convoluted is often the first step in true combatance or vaccines.




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0
 06.13.2012 3:28am


GalaxyHead
Undisguised Man-Made Nova



Headline is misleading. HIV is not AIDS.




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0
 06.13.2012 12:28pm


Magicjewel
Dr. Fantabulous
Administrator



Arckanghel said:

I totally agree that it needs to become more accessible and at a lower cost. However, all the money saved, due to the high cost of HIV/AIDS treatments, might actually land in that bucket for researching a vaccine. A cure, no matter how convoluted is often the first step in true combatance or vaccines.

Actually a cure doesn't really have much to do with vaccines or the development of one.  It's great for treatment of course but vaccine development is in a completely different realm.

I like the premise of this.  It reminds me of some interesting discussions with some fellow studentsI where we surmised that the only way to really get rid of any immunodeficiency was replacing the immune system (aka a bone marrow transplant), which has its own host of potentially lethal problems and actually wouldn't solve all autoimmune diseases (just a lot of them).  The problem with the idea is feasibility, affordability, and availability of donor tissue, as well as the patient's ability to survive after that.

The article doesn't imply that they ablated the existing immune system, but if you look up the details of the case in a scientific journal I would guarantee they ablated most of his immune system.  You pretty much HAVE to for bone marrow transplants, otherwise you will reject the marrow you're transplanting.  The only exceptions might be an autologous transplant (transplant using your own tissue) or possibly an identical twin.  I'm not a transplant expert by any means, but that is my understanding of marrow transplants (and this case was one).

GalaxyHead said:

Headline is misleading. HIV is not AIDS.

Yup.  But a very very common mistake.



"Well, your brain seems to work a little bit." -- Rune Walsh, Phantasy Star IV.




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0
 06.14.2012 6:13am
Thread Creator

Arckanghel
Pirate.



Isn't the headline spot on? They have eliminated this case of AIDS and a currently attempting to complexly verify they have seated the HIV virus in the system.




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